Dr. Till-Hendrik Macher

Publications

2025

  • Macher, T.-H., Beermann, A. J., Arle, J., Foerster, J., Greyer, M., Mora, D., Koschorreck, J., Rolauffs, P., Rother, A., Schüler, S., Zimmermann, J., Hering, D., & Leese, F. (2025). Fit for purpose? Evaluating benthic invertebrate DNA metabarcoding for ecological status class assessment in streams under the Water Framework Directive. Water Research, 272, 122987. https://doi.org/10.1016/j.watres.2024.122987

2024

  • Macher, T.-H., Arle, J., Beermann, A. J., Frank, L., Hupało, K., Koschorreck, J., Schütz, R., & Leese, F. (2024). Is it worth the extra mile? Comparing environmental DNA and RNA metabarcoding for vertebrate and invertebrate biodiversity surveys in a lowland stream. PeerJ, 12, e18016. https://doi.org/10.7717/peerj.18016

2023

  • Macher, T.-H., Schütz, R., Yildiz, A., Beermann, A. J., & Leese, F. (2023). Evaluating five primer pairs for environmental DNA metabarcoding of Central European fish species based on mock communities. Metabarcoding and Metagenomics, 7, e103856. https://doi.org/10.3897/mbmg.7.103856
  • Macher, T.-H., Schütz, R., Hörren, T., Beermann, A. J., & Leese, F. (2023). It’s raining species: Rainwash eDNA metabarcoding as a minimally invasive method to assess tree canopy invertebrate diversity. Environmental DNA, 5(1), 3–11. https://doi.org/10.1002/edn3.372
  • Macher, T.-H., Schütz, R., Beermann, A., Leese, F., Wagner, F., Arle, J., & Koschorreck, J. (2023). Umwelt-DNA-basiertes Monitoring an der Fischtreppe Dessau-Roßlau: Ein Vergleich mit fischereilichen Methoden. Wasserwirtschaft, 113, 47–55. https://doi.org/10.1007/s35147-023-1814-6

2022

  • Hupało, K., Macher, T.-H., Schütz, R., & Leese, F. (2022). Assessing Metropolitan Biodiversity Using Aquatic Environmental DNA Metabarcoding. In J. M. Gurr, R. Parr, & D. Hardt (Eds.), Metropolitan Research (pp. 223–248). transcript Verlag. https://doi.org/10.1515/9783839463109-013
  • Hupało, K., Schmidt, S., Macher, T.-H., Weiss, M., & Leese, F. (2022). Fresh insights into Mediterranean biodiversity: Environmental DNA reveals spatio-temporal patterns of stream invertebrate communities on Sicily. Hydrobiologia, 849(1), 155–173. https://doi.org/10.1007/s10750-021-04718-3
  • Macher, T.-H., Buchner, D., & Leese, F. (2022). APSCALE: Advanced pipeline for simple yet comprehensive analyses of DNA metabarcoding data. Bioinformatics, 38(20), 4817–4819. https://doi.org/10.1093/bioinformatics/btac588

2021

  • Macher, T.-H., Beermann, A. J., & Leese, F. (2021). TaxonTableTools: A comprehensive, platform-independent graphical user interface software to explore and visualise DNA metabarcoding data. Molecular Ecology Resources, 21(5), Article 5. https://doi.org/10.1111/1755-0998.13358
  • Macher, T.-H., Buchner, D., Beermann, A. J., Werner, M.-T., & Leese, F. (2021). Standardized high-throughput biomonitoring using DNA metabarcoding: Strategies for the adoption of automated liquid handlers. Environmental Science and Ecotechnology, 8, 100122. https://doi.org/10.1016/j.ese.2021.100122
  • Macher, T.-H., Schütz, R., Arle, J., Beermann, A. J., Koschorreck, J., & Leese, F. (2021). Beyond fish eDNA metabarcoding: Field replicates disproportionately improve the detection of stream associated vertebrate species. Metabarcoding and Metagenomics, 5, e66557. https://doi.org/10.3897/mbmg.5.66557

2020

  • Beermann, A. J., Leese, F., Macher, T.-H., Buchner, D., Čiampor Jr, F., Čiamporová-Zaťovičová, Z., Cíchová, M., Očadlík, M., Paunović, M., Csányi, B., & Weigand, A. (2020). Metabarcoding of macrozoobenthos samples. Joint Danube Survey 4 Scientific Report: A Shared Analysis of the Danube River. ICPDR Secretariat.
  • Dömel, J. S., Dietz, L., Macher, T.-H., Rozenberg, A., Mayer, C., Spaak, J. M., Melzer, R. R., & Leese, F. (2020). Analyzing drivers of speciation in the Southern Ocean using the sea spider species complex Colossendeis megalonyx as a test case. Polar Biology, 43(4), 319–342. https://doi.org/10.1007/s00300-020-02636-z
  • Hempel, C. A., Peinert, B., Beermann, A. J., Elbrecht, V., Macher, J.-N., Macher, T.-H., Jacobs, G., & Leese, F. (2020). Using Environmental DNA to Monitor the Reintroduction Success of the Rhine Sculpin (Cottus rhenanus) in a Restored Stream. Frontiers in Ecology and Evolution, 8. https://doi.org/10.3389/fevo.2020.00081

2019

  • Dömel, J. S., Macher, T.-H., Dietz, L., Duncan, S., Mayer, C., Rozenberg, A., Wolcott, K., Leese, F., & Melzer, R. R. (2019). Combining morphological and genomic evidence to resolve species diversity and study speciation processes of the Pallenopsis patagonica (Pycnogonida) species complex. Frontiers in Zoology, 16(1), 36. https://doi.org/10.1186/s12983-019-0316-y

2017

  • Macher, J.-N., Macher, T.-H., & Leese, F. (2017). Combining NCBI and BOLD databases for OTU assignment in metabarcoding and metagenomic datasets: The BOLD_NCBI Merger. Metabarcoding and Metagenomics, 1, e22262. https://doi.org/10.3897/mbmg.1.22262

 

Further Publications

  • Macher, T.-H., Beermann, A., Hering, D., & Leese, F. (2024). Abschlussbericht: eDNA-basierte Verfahren in der behördlichen Praxis: GeDNA-Projekt. Im Auftrag des Umweltbundesamtes.
  • Macher, T.-H., Schütz, R., Klümper, L. F., & Leese, F. (2023). Untersuchung zum Vorkommen des Europäischen Schlammpeitzgers (Misgurnus fossilis) im Bereich der Issel, des Wyler Meers und der Heubachniederung mit Hilfe von Umwelt-DNA-Analysen. Technischer Bericht. https://doi.org/10.13140/RG.2.2.32555.25126
  • Macher, T.-H. (2023). DNA metabarcoding for the ecological status assessment in streams - Validation, plausibility check and intercalibration of the new assessment method. https://doi.org/10.13140/RG.2.2.33087.48805